Role of IL-6 and IL-8 polymorphisms in Type I Diabetes mellitus
نویسندگان
چکیده
منابع مشابه
Negative Association of Serum IL-6 and IL-17 with Type-II Diabetes Retinopathy
Background: Diabetes mellitus (DM) is a health concern which leads to complications such as retinopathy. Pakistan has 6.9 million people living with DM and this toll will be doubled by 2025. Objective: To determine serum IL-6 and IL-17 of type 2 diabetes mellitus (T2DM) patients with retinopathy. Methods: In this cross-sectional casecontrol study, 212 subjects enrolled which were categorized in...
متن کاملIL-6, IL-10 and IL-17 Gene Polymorphisms in Iranian Women with Recurrent Miscarriage
Background: Pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (RM). Objective: To investigate the association between RM and five polymorphisms of cytokine genes, interleukin 10 (IL-10), (-592 A/C, -819 C/T, -1082 A/G), IL-6 (-174 C/G) and IL-17 (-197 G/A) in Iranian women. Method: Po...
متن کاملEvaluation of Relation between IL-4 and IFN-y Polymorphisms and Type 2 Diabetes
Objective(s) Although, type 2 diabetes is the most frequent type of diabetes, its main cause is yet to be clarified. Several environmental and genetic parameters are believed to be involved in diabetes. It has also been established that cytokines play key roles in pathogenesis of diabetes. Expression of cytokines is different from person to person and in different societies. Several studies sh...
متن کاملRole of inflammatory mediators (TNF-α, IL-6, CRP), biochemical and hematological parameters in type 2 diabetes mellitus patients of Kashmir, India
Background: Type II Diabetes mellitus (T2DM) is a multifactorial disease and a leading cause of premature deaths. Inflammatory cytokines are reported that they have potential to enhance insulin resistance and hence T2DM. Assessment of immunological profile in T2DM patients of Kashmir valley is unclear. So, detection of cytokines is relevant to determine the extent and direction of immune respon...
متن کاملGenetic polymorphisms of interleukin-1B (IL-1B), IL-6, IL-8, and IL-10 and risk of prostate cancer.
Chronic intraprostatic inflammation is suspected to play a role in the pathogenesis of prostate cancer. Polymorphisms in cytokine genes can influence inflammation and immune response and may be related to the risk of prostate cancer. Four common single nucleotide polymorphisms (SNPs) in the genes encoding interleukin-1B (IL-1B), IL-6, and IL-8 were assessed in 503 prostate cancer cases and 652 ...
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ژورنال
عنوان ژورنال: Medical science
سال: 2023
ISSN: ['2321-7367', '2321-7359']
DOI: https://doi.org/10.54905/disssi/v27i133/e138ms2658